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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCC1
All Species:
3.64
Human Site:
Y736
Identified Species:
7.27
UniProt:
P33527
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.45
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33527
NP_004987.2
1531
171561
Y736
G
C
Q
L
E
E
P
Y
Y
R
S
V
I
Q
A
Chimpanzee
Pan troglodytes
XP_001145351
1247
137800
I495
A
V
Y
S
N
A
D
I
Y
L
F
D
D
P
L
Rhesus Macaque
Macaca mulatta
XP_001094709
1612
178491
R805
G
Q
A
L
N
P
K
R
Y
Q
Q
A
L
E
A
Dog
Lupus familis
XP_548204
1523
168842
R714
G
Q
A
L
D
P
K
R
Y
Q
Q
A
L
K
T
Cat
Felis silvestris
Mouse
Mus musculus
O35379
1528
171166
Y736
G
H
P
L
Q
E
N
Y
Y
K
A
V
M
E
A
Rat
Rattus norvegicus
Q8CG09
1532
171475
C737
G
R
P
L
Q
E
H
C
Y
K
A
V
M
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517193
1537
172363
H747
G
R
Q
P
E
E
R
H
Y
K
Q
V
I
E
A
Chicken
Gallus gallus
Q5F364
1525
170953
R733
G
R
E
M
N
E
S
R
Y
K
R
V
I
E
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001341895
1518
169232
W733
G
R
E
T
K
D
S
W
Y
Q
K
V
V
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_995704
1548
173512
R739
G
Q
T
Y
D
R
K
R
Y
N
K
V
I
D
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42093
1623
182111
K708
G
S
P
F
D
R
E
K
Y
E
R
A
I
D
V
Baker's Yeast
Sacchar. cerevisiae
P39109
1515
171103
F721
G
H
R
Y
D
A
E
F
Y
E
K
T
I
K
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.5
54.1
56.6
N.A.
88.1
87.4
N.A.
84.2
77.6
N.A.
70.5
N.A.
51.2
N.A.
N.A.
N.A.
Protein Similarity:
100
80.1
71
74.1
N.A.
94.7
93.8
N.A.
91.7
89.2
N.A.
83.2
N.A.
68.5
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
26.6
20
N.A.
46.6
40
N.A.
53.3
40
N.A.
26.6
N.A.
33.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
46.6
46.6
N.A.
80
73.3
N.A.
73.3
66.6
N.A.
73.3
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.2
39.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.8
59.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
17
0
0
17
0
0
0
0
17
25
0
0
75
% A
% Cys:
0
9
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
34
9
9
0
0
0
0
9
9
17
0
% D
% Glu:
0
0
17
0
17
42
17
0
0
17
0
0
0
50
0
% E
% Phe:
0
0
0
9
0
0
0
9
0
0
9
0
0
0
0
% F
% Gly:
92
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
17
0
0
0
0
9
9
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
9
0
0
0
0
50
0
0
% I
% Lys:
0
0
0
0
9
0
25
9
0
34
25
0
0
17
0
% K
% Leu:
0
0
0
42
0
0
0
0
0
9
0
0
17
0
9
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
17
0
0
% M
% Asn:
0
0
0
0
25
0
9
0
0
9
0
0
0
0
0
% N
% Pro:
0
0
25
9
0
17
9
0
0
0
0
0
0
9
0
% P
% Gln:
0
25
17
0
17
0
0
0
0
25
25
0
0
9
0
% Q
% Arg:
0
34
9
0
0
17
9
34
0
9
17
0
0
0
0
% R
% Ser:
0
9
0
9
0
0
17
0
0
0
9
0
0
0
0
% S
% Thr:
0
0
9
9
0
0
0
0
0
0
0
9
0
0
9
% T
% Val:
0
9
0
0
0
0
0
0
0
0
0
59
9
0
9
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
17
0
0
0
17
100
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _